Mexican cavefish
Credit: Colin Beesley
Outline
Originated from surface-dwelling fish; some populations adapted to dark cave environments, becoming eyeless and pigment-less
Both surface fish and cavefish are the same species, but show major physiological and genetic differences
Some cave populations regained regenerative abilities, unlike their surface counterparts
Offers a unique opportunity for intra-species comparison: studying gene expression differences between regenerative and non-regenerative populations
Helps pinpoint genes that are upregulated or downregulated during the evolution of regeneration
A powerful model for exploring how environmental pressures drive genetic changes in regeneration